突破性艾滋病新药：三名携带HIV婴儿被治愈

2014年07月05日 10:39 参考消息网

说明：引用本文时，为了更客观，我在“治愈”两字上加了引号。不过，这也已经是很令人兴奋的消息了。

参考消息网7月4日报道 英国《每日邮报》网站7月1日发表题为《3名携带HIV病毒的婴儿在出生几小时后接种突破性疫苗终被治愈》的报道称，3名在出生仅几小时后就接受一种突破性新药治疗的婴儿被宣布不再携带艾滋病病毒(HIV)。还有一名婴儿在接受同样治疗后体内病毒浓度变得非常低。

这项发现将于20日在墨尔本召开的2014年国际艾滋病大会上宣布。在与艾滋病的斗争中，这是一项重大突破。科学家希望，如果治疗时间足够早，该病能够治愈。

尚不清楚这几名婴儿现在有多大了。不过，在来自近200个国家的1.4万名代表来到墨尔本交流在该领域的研究成果和最新科学进展时，预计会公布更多情况。

本届大会的主席之一莎伦·卢因教授说：“这一结果让我们很兴奋，因为4名婴儿都在出生后不久就接受了治疗，实际上在这些婴儿的身体系统内已找不到病毒了。这几名婴儿的病例，还有更多的成人病例告诉我们，如果治疗开始得非常早，我们是能阻止一些人体内的HIV的。但必须牢记，防止婴儿感染HIV的最好办法是在母亲怀孕时接受治疗。”

这4名经母婴传播感染HIV的在加拿大出生的婴儿，接受了3种高剂量抗逆转录病毒药物的治疗。

中文消息链接： http://tech.sina.com.cn/d/2014-07-05/10399477843.shtml

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英文网站原文链接：http://www.dailymail.co.uk/news/article-2676037/Four-babies-CURED-HIV-given-revolutionary-vaccine-hours-lives.html

Three babies 'CURED' of HIV after being given revolutionary vaccine in the first hours of their lives

• Three Canadian born babies have been declared HIV-free after receiving treatment straight after their births

• The method was adopted by the doctors after a similar case led to an infant in Mississippi being cured of the virus in 2013
  

• The major breakthroughs will be discussed at the AIDS conference in Melbourne from July 20-25
  

By Lillian Radulova

Published: 05:19 GMT, 1 July 2014 | Updated: 07:46 GMT, 1 July 2014

Three babies have been declared HIV-free after being treated with a revolutionary new drug only hours after they were born.

The fourth child only has 'a very low level' of the virus after receiving the same treatment.

The findings, to be announced at the AIDS 2014 conference in Melbourne from July 20, are a major breakthrough in the fight against AIDS with scientists hoping it could lead to a cure if treatment his received early enough.

Four Canadian babies have been cleared of having HIV after being born to HIV-positive mothers, due to being given a high dose of three different antiretroviral drugs

It's not yet known how old the babies are now but more is expected to be released when 14,000 delegates from nearly 200 countries descend on Melbourne to share their research and the latest scientific advances in the field.

AIDS 2014 co-chairman, Professor Sharon Lewin, told the Daily Mail Australia that despite some people labelling the results as a 'cure', it can not yet be officially classed as one.

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'At the moment, the doctors do not know whether they are in fact cured. The only way they can tell is if they stop the anti-HIV drugs and see if it comes back,' Professor Lewin said.

'We are excited about this though because all four received very early treatment after delivery, and when doctors tried to locate the virus they could find virtually no viruses in their systems.

'These baby cases, and more cases amongst adults, tell us that if we treat HIV very early in some people were able to stop it.

News of the four babies and their success stories comes only a year after the very first child to ever be 'cured' of HIV was officially announced.

'And in some people, maybe only 10 per cent or so who start treatment very early, it might even be safe for them to stop taking their drugs and their virus stays under control. However this is still a research question that needs to be addressed.'

'However you must keep in mind that the best way to stop babies getting HIV is to treat the mother during pregnancy,' she added.

After contracting the virus from their mothers, the four Canadian-born children were given a high dose of three different antiretroviral drugs.

News of the four babies and their success stories comes only a year after the very first child to ever be 'cured' of HIV was officially announced.

The baby, born in Mississippi in 2010, and was cleared of any infection in 2013.

The mother of the child only found out that she was infected with HIV during her labor and thus was not able to take precautionary action which could help her unborn child avoid infection.

The major breakthrough will be discussed amongst a whole range of other new research at the AIDS conference in Melbourne from July 20-25

According to the University of Mississippi, Dr. Hannah Gay associate professor of pediatrics and a HIV specialist, gave the baby a three-drug antiretroviral therapeutic prescription, beginning the treatment when she was only 30-hours-old - despite not having confirmation that the baby was infected at the time.

Only 29 days later, the virus could not be found in the infant's system and did not return after the child stopped taking her prescription.

However the four Canadian children are yet to stop taking their treatment and doctors are unable to determine if the virus is likely to return if they do.

In 2009, an American man called Timothy Ray Brown received bone marrow from a donor who was resistant to HIV and was later given the all-clear by a Berlin hospital.