【陈永】遵医附院 - 风湿免疫科 - 医生门诊时间 - 预约挂号 - 在线问诊

擅长

红斑狼疮，类风湿，强直性脊柱炎，痛风。特别是：复发性难治性口腔溃疡、白塞病、老年风湿病（自身免疫性疾病）

简介

男，江苏淮阴人。复旦大学医学博士，内科学主治医师，风湿病学副主任医师，研究生导师。
本科毕业于贵阳医学院（现贵州医科大学）临床医学学士、硕士毕业于江西中医药大学中医学、博士毕业于复旦大学内科学（风湿病学）师从管剑龙教授、于南方医科大学中西医结合医院博士后，导师肖长虹教授。目前就职于深圳市人民医院风湿免疫科。
参与国家级，省级自然科技研究8项，先后在国内外医学核心期刊发表医学论文58余篇，其中SCI论文9篇，被引用120余次。硕士、博士研究生国家奖学金获得者；复旦大学光华奖学金获得者。休斯顿.美国2014年整合医学学术研讨会优秀讲者。主张整合医学，用西医现代科学技术研究中医基础理论，发现高血压、心脑血管疾病、糖尿病、胃肠道溃疡、癌症等在发病机制上有着共同的信号传导通路，多种老年性疾病的发病与名医朱丹溪“人体阴常不足，阳常有余”有着密切联系。从而提出多种老年性疾病的发病现代医学机制与阴常不足，阳常有余的紧密结合，挖掘朱丹溪宝贵治疗经验。
致力于整合医学处理内科学疾病。整合医学是一门新兴学科：不仅运用现代医学疗法，还结合各种疗法综合有机运用；不仅注重疾病的治疗，也注重全身的康复；注重医患关系的维护。“尽我所学，贡献微薄之力，促进您早日康复。” 擅长：免疫风湿科疾病，类风湿性关节炎，老年性关节炎，干燥综合征，系统性红斑狼疮，强直性脊柱炎，白塞病，癌症康复、银屑病、消化系统溃疡等，主张Make incurable diseases curable（将不能治愈的疾病治愈）。获得病人广泛好评。

Male, Born in Jiangsu Huaiyin. Doctor of Medicine, Fudan University, Internal Medicine Physician. Now he is a postdoctoral fellow at the Integrative Medicine Hospital of Southern Medical University.
Bachelor degree in Clinical Medicine from Guiyang Medical College (now Guizhou Medical University), graduated from Jiangxi University of Traditional Chinese Medicine, Chinese Medicine, Ph.D. in Fudan University, Department of Internal Medicine (Rheumatology), Professor Guan Jianlong, working in Southern Medicine Postdoctoral fellow of the University of Integrated Traditional Chinese and Western Medicine.
Participated in 8 national and provincial natural science and technology researches, and published more than 58 medical papers in medical core journals at home and abroad, including 9 SCI papers, which were cited more than 120 times. Master's and doctoral students' national scholarship winners; Fudan University Guanghua Scholarship winners. Excellent speaker at the 2014 American Integrative Medicine Symposium in Houston. Advocating integrated medicine, using Western medicine modern science and technology to study the basic theory of traditional Chinese medicine, found that hypertension, cardiovascular and cerebrovascular diseases, diabetes, gastrointestinal ulcers, cancer, etc. have a common signaling pathway in the pathogenesis, the incidence of various senile diseases With the famous doctor Zhu Danxi, "the human body is often inadequate, and the yang is always more than enough". Therefore, the modern medical mechanism of the onset of various senile diseases is not enough, and the yang often has more close integration, and the valuable treatment experience of Zhu Danxi is explored.
Committed to integrating medical treatment of internal medicine diseases. Integrated medicine is a new subject: not only the use of modern medical therapy, but also the comprehensive use of various therapies; not only the treatment of disease, but also the rehabilitation of the whole body; pay attention to the maintenance of the relationship between doctors and patients. "Do my best, contribute to the meager strength, and promote your early recovery." Good at: immune rheumatology, rheumatoid arthritis, senile arthritis, Sjogren's syndrome, systemic lupus erythematosus, ankylosing spondylitis, white Plug disease, cancer rehabilitation, psoriasis, digestive system ulcers, etc., advocate Make incurable diseases curable (to cure a disease that cannot be cured). Received wide acclaim from patients.

社会任职

贵州省高层次引进人才
遵义市健康科普专家
贵州省中医药学会风湿病分会常务委员
毕节市七星关区中医妇幼集团医院副院长
毕节市科技特派员
深圳大学华南医院特聘副研究员
广东省省老年保协会自血穴位注射疗法专业委员会常务委员

获奖荣誉

1.国家硕士奖学金，2014
2.复旦大学优秀学生，2018
复旦大学光华奖学金，2016
4. 博士研究生国家奖学金，2017
5. 复旦大学“我的医学，我的梦”，三等奖，2017
6.复旦大学临床前沿博士论坛，三等奖，2017
7.中国中西医结合风湿病学术年会，优秀奖，2018
8.上海中医药大学研究生论坛，二等奖，2023
9.贵州省高层次引进人才：2023

科研成果

主持或参与的科研项目（课题）Research projects
(1)广东省中医药局科研项目，青年项目，20201229 ，三水白虎汤药物血清对类风湿关节炎FLS的AIM-2炎症小体通路影响，2020-01至2021-12，1.0万元，结题，主持。
(2)广东省医学科研基金项目，立项资助，A2019053， AMPK通路依赖的IL-17在RA患者滑膜成纤维细胞增生中的机制，2019-07至2021-06，0.5万元，结题，主持。
(3)国家自然科学基金员会，面上项目，81871276，干扰素调节因子8通过RORrt通路调控T h17 细胞分化在白塞病发病机制中的作用，2018.01-2022.12，56万元，结题，参加。
（4）中国博士后科学基金，面上项目，2021M701438，基于AMPK-代谢/炎症通路探索甘草养阴汤（自拟方）对老年类风湿关节炎的作用机制及应用价值，2021-2023,8万元，结题主持。
（5）深圳市科创委，基础研究（面上项目）；调控肿瘤微环境的智能型纳米药物抑制肝癌微波消融后复发进展的研究，2021-2023,15万元，参与。
（6）深圳市科创委，基础研究（面上项目）JCYJ20220530152204011；牙龈卟啉单胞菌上调巨噬细胞sPD-1表达促进类风湿关节炎的机制研究，2021-2023,15万元，参与。
(7)国家自然科学基金员会，面上项目，8207140664，三水白虎汤阻断滑膜成纤维细胞炎症记忆治疗顽固性类风湿关节炎的机制研究，2021.01-2024.12，55万元，结题，参加。
（8）国家自然科学基金员会，地区基金，82460325，RA滑膜成纤维细胞分泌HAPLN1通过PI3K/AKT/mTOR信号调控巨噬细胞极化促进滑膜炎症的作用机制，2025.01-2027.12，34万元，在研，主持。
（9）贵州省中医药管理局，编号：QZYY-2025-004，甘草养阴汤通过PI3K/AKT通路调节“炎症性衰老”在衰老RA模型中的作用机制研究，2025-01-01至2025-12-30，在研，主持。
（10）贵州省基础研究计划（自然科学）青年引导项目合同编号：黔科合基础-[2024]青年307（QKHJC [2024] Youth 307）。探索甘草养阴汤通过Pi3k/Akt通路调节“炎症性衰老”在衰老RA模型中的作用机制。2024-08-01到2027-07-31，5万元，在研，主持。
（11）贵州省卫生健康科研项目，编号：gzwkj2025-002，HAPLN1通过PI3K-Akt信号通路对类风湿关节炎滑膜巨噬细胞影响研究，2024-06-01 至 2026-12-31，2万元，在研，主持。
（12）贵州省卫生健康科研项目，编号：gzwkj2024-126，消瘦对CIA模型脂代谢-炎症反应的影响。2024-01-01 至 2025-12-31，，在研，主持。
（13）遵义医科大学附属医院博士科研启动资金编号：院字2023（03）号（YZ-2023 (03)），联合甘草养阴汤的中西医结合方案治疗老年类风湿性关节炎：临床真实世界研究。2023.5-2027.5，在研，主持。
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[19] Chen Y, Luo D, Cai J F, et al. Effectiveness and safety of Glycyrrhizae Decoction for Purging Stomach-Fire in Behcet disease patients: Study protocol for a randomized controlled and double-blinding trail[J]. Medicine (Baltimore),2018,97(13):e265.
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[21] Chen Y, Guan J L. Is Warfarin Indicated in Behcet's Syndrome Associated with Thrombosis? Reflections on Treatment and Death of a Patient[J]. Chinese Medical Journal,2018,131(1):105-106.
[22] Chen Y, Cui J S, Cai J F, et al. Surgical Intervention for Behcet's Disease with Aorta Aneurysm and Pseudoaneurysm: Opposite Outcomes in Two Cases[J]. 中华医学杂志(英文版),2017,130(20):2503.
[23] Chen Y, Gu F, Guan J. Metformin Might Inhibit Virus through Increasing Insulin Sensitivity[J]. Chinese Medical Journal,2018,131(3):376-377.
[24] Yong C, Jian-Long G. Reply to "Comment to Deep vein thrombosis induced by vasculitis in the Behcet's syndrome"[J]. 中华医学杂志英文版,2019(4):503-504.
[25] Chen Y, Zheng J, Fang J, et al. Application of “Monarch, Minister, Assistant and Envoy” Principle to Rheumatoid Arthritis Management[J]. J Rheumatol Arthritic Dis,2017,3(3):1-4.
[26] Pan R, Chen Y, Nandakumar K S, et al. Gancao Nurish-Yin Decoction medicated serum inhibits growth and migration of ovarian cancer cells: Network pharmacology-based analysis and biological validation[J]. Pharmacological Research - Modern Chinese Medicine,2022,2:100062.
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[30] Yan S H, Chen Y, Huang Z Q, et al. Acupoint Autohemotherapy Attenuates DNCB-Induced Atopic Dermatitis and Activates Regulatory T Cells in BALB/c Mice[J]. J Inflamm Res,2024,17:2839-2850.
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[33] Jing-Fen Y M S, Chen Y, Cai J F, et al. Incidence and risk factors for anemia among newly-diagnosed intestinal Behcet's disease patients[J]. Journal of the National Medical Association,2019,111(4):407-412.
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[35] Chen Y, Zhang Y. Interpretation of the Pathological Mechanism of Blood Stasis in Traditional Chinese Medicine in Light of Understanding of Hypercoagulable States in Modern Medicine[J]. Chinese medicine and natural products,2025,05(01):e30-e34.
[36] 贺漭，陈永，陈艳娟，等. 甘草养阴汤干预类风湿性关节炎的价值研究[J]. 遵义医科大学学报,2024,47(06):603-609.
[37] 陈永，陈艳娟，刘冬舟. 甘草养阴汤对老年类风湿关节炎的价值探索[J]. 中医药临床杂志,2022,34(03):491-497.
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[39] 吴惠梅，陈永，肖长虹，等. 甘草养阴汤在改善小鼠银屑病样皮损和调节炎症反应中的作用[J]. 天津中医药大学学报,2022,41(04):457-464.
[40] 陈永，汪保江，宋文聪，等. 基于转录组测序技术研究甘草养阴汤增强衰老MH7A细胞活力[J]. 现代中药研究与实践,2022,36(04):18-23.
[41] 罗成根，黄坤，潘小丽，等. 类风湿关节炎滑膜成纤维细胞分泌的HAPLN1促进巨噬细胞向M1型极化[J]. 细胞与分子免疫学杂志,2025,41(5):413-419.
[42] 赵莉，陈艳娟，彭锐，等. 健康成年女性人群中体重指数、瘦素与代谢-炎症性衰老的相关性[J]. 海军军医大学学报,2022,43(09):1029-1036.
[43] 陈永，陆芳，管剑龙. 白塞病进展累及中枢神经1例报告[J]. 南方医科大学学报,2016,36(12):1737-1739.
[44] 陈永，邱富娟，肖长虹. 类风湿性关节炎患者血浆腺苷酸活化蛋白激酶(AMPK)水平升高并与疾病活动度呈正相关[J]. 细胞与分子免疫学杂志,2020,36(05):438-443.
[45] 陈永，邱富娟，朱兴旺，等. 血管翳并非类风湿关节炎的专利—膝骨关节炎血管翳病理形态观察[J]. 南方医科大学学报,2019,39(06):747-750.
[46] 陈永，宣亚男，陈艳娟，等. 白蛋白/球蛋白与类风湿性关节炎患者的DAS28和ESR水平呈负相关[J]. 暨南大学学报：自然科学与医学版,2019,40(5):373-382.
[47] 陈永，罗丹，管剑龙. 抗风湿药联合重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白治疗类风湿关节炎致肺部重度感染死亡一例[J]. 中华老年医学杂志,2017,36(10):1143-1146.
[48] 陈永，刘文静，邹峻，等. 白塞病合并肠道病变的临床回顾性分析[J]. 复旦学报(医学版),2017,44(04):493-497.
[49] 王慧，陈永，管剑龙. 视黄酸在免疫调节中的研究进展[J]. 实用药物与临床,2017,20(09):1102-1105.
[50] 陈永，管剑龙. 风湿性疾病血清维生素A水平下降[J]. 中国免疫学杂志,2017,33(07):1068-1071.
[51] 陈永，管剑龙. MAGIC综合征1例报告[J]. 第二军医大学学报,2017,38(10):1348-1349.
[52] 陈永，蔡剑飞，管剑龙. 肠型白塞病合并带状疱疹1例及相关文献复习[J]. 疑难病杂志,2016,15(06):642-643.
[53] 陈永，鲍华芳，蔡剑飞，等. 酷似白塞病三联征的副肿瘤天疱疮一例[J]. 中华医学杂志,2017,97(41):3276-3277.
[54] 陈永，管剑龙. 调节性T细胞与白塞病[J]. 暨南大学学报：自然科学与医学版,2016,37(2):116-121.
[55] 陈永，王慧，管剑龙. 甘草泻心汤治疗白塞病的近10年研究概览[J]. 时珍国医国药,2018,29(02):412-414.
[56] 陈永，李亚明，管剑龙. 白塞病的中西医结合病理机制[J]. 中国中医基础医学杂志,2018,24(01):28-30.
[57] 陈永，管剑龙. 类风湿关节炎合并白塞病1例[J]. 复旦学报(医学版),2018,45(01):140-142.
[58] 陈永，管剑龙. 类风湿关节炎用药的“君臣佐使”概念[J]. 复旦学报(医学版),2018,45(03):433-435.
[59] 陈永，蔡剑飞，邹峻，等. 中医脾实质乃“pancreas”而非“spleen”[J]. 医学争鸣,2017,8(01):35-38.
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[61] 陈永，罗丹，邹峻，等. 二甲双胍干预皮肤黏膜型白塞病的前瞻性临床研究[J]. 暨南大学学报(自然科学与医学版),2016,37(05):372-377.
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